By working directly with industry, NRG researchers adapt and provide innovative science-based solutions to the challenges and opportunities that emerge in a changing market. Certifying that regulatory compliance is met with every project, NRG’s multidisciplinary team ensures that companies using NRG’s services are educated on the latest quality standards and technological advances.
If you have a potential project in mind, ask an NRG research expert.
Email: Paula_Brown@bcit.ca
Dr. Paula Brown is the Director of BCIT’s Natural Health and Food Products Research Group (NRG), which has been actively supporting the Natural Health Products (NHP) industry for over two decades through applied research activities, including product development, establishment of quality standards and regulatory compliance. Dr. Brown is also the Tier 2 Canada Research Chair in Phytoanalytics, investigating the wide range of chemicals produced by plants, how they are synthesized, regulated and allocated within plant tissues, their extractability and activity and their role in plant and human health.
Key areas
- Mass spectrometry, high-performance liquid chromatography, analytical method development, chemometrics
- Natural product chemistry, validation studies, plant metabolomics
Education
PhD, Chemistry, University of British Columbia
MSc, Chemistry, Simon Fraser University
BSc Honours, Chemistry & Biochemistry, Dalhousie University
Awards
American Botanical Council Norman R. Farnsworth Excellence in Botanical Research. 2021
Award First Place Blue Ribbon. American Urological Association. 2016
Neil Towers Award. Natural Health Product Research Society of Canada. 2016
Herbal Insight Award. American Herbal Products Association. 2016
Thieme Award for the Most Innovative Planta Medica Original Paper. 2013
Committees
- Dietary Supplement Joint Committee (NSF)
- Analytical Laboratories and Botanical Raw Material Committees (American Herbal Products Association)
- Advisory Board of the American Botanical Council
- Natural Health Products Program Advisory Committee (PAC)
- Two grant review committees for National Center for Complementary & Alternative Medicine, NIH
- AOAC International:
- Referee for the Dietary Supplement Methods Committee 2004-2009
- Member of the Dietary Supplement Task Force (2003-present)
- Participated on seven Expert Review Panels
- Directed four full collaborative studies: Goldenseal (Official Methods SM 2008-04), Ginseng (SM 2008-05), Kavalactones, and Echinacea (in review).
- Approved methods: Curcuminoids in Turmeric, Kombucha, Mitragyna speciosa (Kratom), Goldenseal.
- Founding Director of the NHP Research Society of Canada (2003)
Publications
Research News
- BCIT researcher Dr. Paula Brown awarded the ABC Norman R. Farnsworth Award. BCIT News, June 7, 2021.
- Kombucha: an alcoholic or non-alcoholic beverage?. BCIT News, Nov 1, 2019.
- BCIT Researchers have received Official Method of Analysis status for cannabinoids in cannabis. BCIT News, Apr 19, 2019.
- Cannabis beverages in the brew: BCIT and UBC partner with private cannabis company. BCIT News, November 28, 2018.
- High-tech cannabis research supports quality control. BCIT News. May 10, 2018.
- Vancouver researchers take issue with U.S. FDA’s alarmist memo on kratom. Georgia Straight. February 17, 2018.
- Visiting Professor of Pharmacy Science of Hunan University of Chinese Medicine
- Member, Natural Health Products Program Advisory Committee (PAC), Chair, Product Testing Working Group, convened to make recommendations on policy related to standards of evidence for quality. The mandate of the PAC is to provide the NHP Program Directorates ( Natural Health Products Directorate, Marketed Health Products Directorate and Health Products and Food Branch Inspectorate ) with advice and recommendations on current and emerging issues relevant to the Canadian regulatory framework for natural health products.
Research Collaborators
Wendy Applequist. Missouri Botanical Garden
Joseph M Betz. National Institutes of Health, Office of Dietary Supplements
Mark Blumenthal. American Botanical Council
Michael Deyholos. Biology, UBC
Susie Finlay. Vancouver Community College
Roy Golsteyn. University of Lethbridge
Loren Israelson. United Natural Products Alliance
A. Max P. Jones. Plant Agriculture, Guelph
Ikhlas Khan. Director, National Center for Natural Products Research
Danna Leeman. Canadian Museum of Nature
Susan J. Murch. Chemistry, UBC
Diane Ragone. National Tropical Botanical Garden, Kauai, Hawaii
Mark Rheault. Biology, UBC
Praveen K. Saxena. Plant Agriculture, Guelph
Paul R. Shipley. Chemistry, UBC
Roy Upton. American Herbal Pharmacopoeia
Peter Wentzell. Department of Chemistry, Dalhousie University
Industry
- West Kootenay Herb Grower’s Cooperative
- Natural Factors
- Joy of the Mountains
- Happy Planet
- CMH Biotechnolgies
- Jamieson Labs
Community
- BC Food Processors Association
- Small Scale Food Processors Association of BC
- Canadian Health Food Association
Student Researchers
- I. Cole, UBC Biology
- Elizabeth Mudge, BCIT
- J. Lund, UBC Chemistry
- Dr. C. Turi, University of Guelph
- Dr. Y. Liu, BCIT
Research Centres
Email: mohamed_albadry@bcit.ca
Mohamed joined BCIT’s Natural Health and Food Products Research Group in 2021 to conduct research in the discovery and function of natural products from natural sources in projects jointly supervised by Dr. Paula Brown. Mohamed also works with Dr. Michael Deyholos, the head of the Department of Biology at the University of British Columbia.
Mohamed has a lifelong passion for natural products and their immense role in improving the life of human beings. For him, working in natural products’ research is a fine art that he excels in and has enjoyed throughout his career. To succeed in such a multidisciplinary area of research he has developed the skills of isolation, structure elucidation of bioactive metabolites, and the use of total synthesis as a powerful tool for supplying rare drug leads not available in sufficient quantities from nature.
In his previous postdoctoral experience at the National Center for Natural Products Research, University of Mississippi, he worked on projects to develop analytical methods and reference standards for the standardization of some pharmaceuticals, dietary supplements, and agrochemicals, in addition to evaluation of botanicals’ utility in the dietary supplements industry by using multiple techniques for the identification and authentication of medicinal plants.
Mohamed received his PhD in Pharmacognosy from the department of BioMolecular Sciences at the University of Mississippi. He also holds an M.Sc. in Pharmaceutical Sciences with emphasis in Pharmacognosy and B.Sc. in Pharmacy and Pharmaceutical Sciences from Al-Azhar University, Faculty of Pharmacy, Cairo, Egypt.
Email: Michael_Chan@bcit.ca
Michael Chan has been a researcher with BCIT’s Natural Health and Food Products Research Group since 2004. Michael received his PhD in Pharmacognosy from the University of Mississippi and also holds a BSc in General Sciences from the University of British Columbia, a BTech in Environmental Health from BCIT and a DTech in Food Technology from BCIT.
Michael has extensive knowledge and experience in areas related to the chemical and biological aspects of pharmacognosy, including bioassay design and applications, analysis of natural products in complex matrixes, isolation techniques, and methods for the determination of unknown chemical structures.
During his time in the department, Michael has worked on a variety of projects focused on the development, assessment and assurance of the quality, safety and efficacy of dietary supplement, natural health and food products. With his knowledge and experience in regulatory affairs and risk assessment, Michael has also coordinated several projects focused on the regulatory compliance of dietary supplements, natural health and food products.
Email: Jamie_Finley@bcit.ca
Jamie Finley is a research assistant with BCIT’s Natural Health and Food Products Research Group (NRG). He has a keen interest in applying multivariate data analysis to natural health product quality and has over 7 years experience in microbiology and analytical chemistry. Jamie is also one of NRG’s specialists in fermentation, identification of micro-organisms and microbial load criteria for agricultural products. Jamie’s overall goal at NRG is to advance the state of practice for characterization and quality control of commercial and research based natural health products.
Jamie began his career as a co-operative student with the UBC Michael Smith Laboratories and BCIT’s NRG. He then went on to characterize lipids, plasmid DNA and siRNA for a leading molecular therapeutics company and was involved in developing chemical characterization methods for therapeutic study. Prior to joining NRG full time, Jamie worked as a microbiologist for a leading BC analytical laboratory where he analyzed the microbiological and chemical parameters of different materials.
Jamie has a BSc (Hons) and DiplT in biotechnology from UBC and BCIT. He is able to conduct business in American Sign Language and is a member of AOAC International.
Email: yliu298@bcit.ca
Dr. Ying Liu joined the Natural Health and Food Products Research Group (NRG) in 2016. Dr. Liu has a BSc in Plant Science from Dalhousie University and a Ph.D. in Biochemistry and Molecular Biology from the University of British Columbia. Dr. Liu’s research focuses on the utilization of traditional plants and medicinal herbs for food security, human nutrition, and human health.
One of Dr. Liu’s major roles in NRG is to develop and validate analytical methods for measuring phytochemicals in complex matrices, including plants, commercial products, and biological samples. Dr. Liu’s first published method validation has been approved as Final Action Official Method of Analysis 2016.12 Determination of Ethanol in Kombucha Products, which led to collaboration with the BC Centre for Disease Control. Her research has contributed to 8 new ingredients for food and cosmetic products including approvals for a New Dietary Ingredient in Canada and Generally Recognized as Safe Status in the US during her Ph.D.
Her other research interest is the use of metabolomics profiling combined with multivariate data analysis as an innovative way to assess plant biochemical composition. This application has been proven effective in discovering novel plant compounds and identifying plant authenticity.
She is currently involved in several formulations and product development projects, trying to maximize plant utilization as bioproducts through the use of emulsions and nanotechnology in the hope to improve solubility, stability, and delivery of key ingredients with industrial application in food and self-care products.
Dr. Liu is currently on leave.
Email: Hazrah_Moothoo@bcit.ca
Hazrah Moothoo is a multi-talented research assistant with BCIT’s Natural Health and Food Products Research Group (NRG). She has worked with NRG since 2001 and has developed a strong skill set in plant collection, macroscopy and microscopy. Hazrah also coordinates many of NRG’s research projects and is the key contributor to most operations. Hazrah has a BSc in biology from SFU and a DiplT in biotechnology from BCIT. Prior to joining NRG, Hazrah gained experience in a variety of industry laboratory positions. She began her career in the biosciences as a research assistant working as part of a therapeutic drug monitoring program team and continued in industry analyzing pesticide residues in food materials.
Hazrah assisted in the preparation of course and laboratory materials for BCIT’s Food 1190 – Herbal Product Quality. The course was designed to provide practical training in microscopic/macroscopic skills for companies to create a quality control program to support Health Canada’s NHP Regulations established in 2004. As a member of board for the BC Herb Growers Association from 2004-2006, Hazrah was also instrumental in securing funding from the Health Product and Functional Food Program (BC Innovation Council) to revitalize the Association’s marketing approach.
Hazrah completed a professional development leave in 2011 where she was invited to conduct field collections of Crataegus species in the Pacific Northwest as part of an NSERC funded research project with the Royal Ontario Museum. As a visiting scholar with University of Mississippi’s Maynard W. Quimby Medicinal Plant Garden, Hazrah assisted in the cultivation of trial plots of 3 types of chamomile to support research projects conducted by the School of Pharmacy. Hazrah has completed the Associate Certificate in Leadership at BCIT.
Email: Rebecca_Robertson@bcit.ca
Rebecca Robertson graduated from UBC with a BSc in Microbiology. Rebecca brings extensive industry experience to BCIT having established and operated a business partnership offering technical consulting to the food and NHP industry for 15 years.
Areas of expertise include HACCP Plan development and implementation, product development, and education and training. Rebecca’s projects combine science and business as this is the key to offering practical, economical solutions that work in a business context. This combination of expertise reside in BCIT meaning that collaborative projects can be created in-house.
HACCP Plan implementation is an area of specialty; in particular the Hazard Analysis and the integration of HACCP into a business context. Food safety and shelf-life evaluations are also a specialty allowing processors to bring new products to market with confidence and knowledge.
Rebecca coordinates and maintains BCIT’s food industry short courses. She looks forward to expanding BCIT’s course offerings such that that the industry will continue to have the education and training needed to ensure the production of safe products that meet quality standards.
Email: anika_singh@bcit.ca
Dr. Anika Singh joined the Natural Health and Food Product Research Group (NRG) in 2021 as Project Leader. She is an active researcher working in the interface of Post-Harvest Processing and Food Chemistry and helping Canadian Food Industries solve R&D challenges. Before joining NRG, Dr. Singh worked as a Research Associate at the Faculty of Land and Food Systems, University of British Columbia (UBC). At UBC, Dr. Singh contributed significantly to the development of collaborative research projects and the implementation of innovative research strategies and managing research partnerships between local BC food industries, government, and academia.
Dr. Singh received her PhD degree in Food Science from McGill University in 2016. Soon after finishing her PhD, Dr. Singh won the Talent Edge Fellowship in Ontario, Canada, and was appointed as a Manager of Compliance & Technical Services at Allergen Control Group (ACG), Toronto. At ACG, Anika worked with food safety regulators and enforcement agencies around the globe to harmonize the standard against management certification of facilitates producing gluten-free food products. She has extensive work experience in various novel food processing techniques such as thermal, high pressure, pulsed light & microwave processing and has researched food safety and microbial validation. Dr. Singh is an expert in food quality and safety with working knowledge of Canadian & US food & drug regulations and food quality/safety policies. She has more than 35+ publications in renowned journals in food science and presentations at international conferences.
Key research areas
Post-Harvest Processing, Food Chemistry, Bioaccessibility and Bioavailability of Bioactives, Digestion of Food and Natural Health Products, Food Emulsions, Packaging Film Design, HPLC and GC Analysis of Food Components, Process Machinery Design.
Education
PhD, Food Science, McGill University, Canada
M.Tech, Post Harvest Processing and Food Engineering, Jawaharlal Nehru Agriculture University, India
B.Tech, Agriculture Engineering, Jawaharlal Nehru Agriculture University, India
Publications
View a list of current publications
Email: Hong_Sy@bcit.ca
Hong has been a Research Analyst with the BC Institute of Technology’s (BCIT) Natural Health and Foods Products Research Group (NRG) since September 2010. With over 10 years’ experience in the food technology industry she brings to the group hands on experience with HACCP, SOP’s, GMP’s and regulatory compliance. During her time here she has worked closely with food manufactures to implement practical HACCP programs that integrate into operations. She has been assisting industry in the commercialization and development of new food products and has helped companies improve existing processes to find efficiencies within their manufacturing process. Hong has also developed curriculum for industry related HACCP courses such as Environmental Monitoring and Thermal Processing in the part time studies area at BCIT.
Prior to joining NRG, Hong began her career in the food manufacturing industry as a quality control technician in the meat industry. In 2007, she completed the professional Culinary Diploma at the Northwest Culinary Academy of Vancouver. Upon completion of the program she moved into product development roles at major local food companies in the lower mainland.
Currently she is enrolled in the Operation Management Lean Six Sigma Associate Certificate within the School of Business.
Email: Ronan_Yu@bcit.ca
As research assistant with BCIT’s Natural Health and Food Products Research Group (NRG), Ronan Yu has thorough knowledge in the field of natural product research. With over 10 years experience in molecular biology and analytical chemistry, he is one of NRG’s specialists in the development and validation of analytical test methods. Ronan’s advanced instrumentation skills and ability to adapt new technologies to the analysis of natural health products are key assets to the success of NRG.
Prior to joining NRG, Ronan worked in a variety of industry and government positions. He began his career in the biosciences as a junior microbiologist investigating fungal wood rot for Forintek and continued as a researcher investigating pathogenic organisms in stock feedlot for Agriculture and Agri-Food Canada. Ronan branched into the field of analytical chemistry while conducting trace metal analysis at Philip Analytical Services and went on to validate analytical methods for drug analysis at Angiotech.
Ronan has a BSc (Hons) in biotechnology from UBC and a DiplT in both chemical sciences and biotechnology from BCIT. He is fluent in Tagalog (Filipino) and is an active member of the NHP Research Society.
Email: Xiaohui_Zhang@bcit.ca
As a research analyst with BCIT’s Natural Health and Food Products Research Group (NRG), Xiaohui Zhang is contributing his strong expertise in medicinal chemistry to the field of natural health products. With over 13 years of experience in chemistry, he is one of NRG’s specialists in organic synthesis and phytochemical investigation. Xiaohui’s advanced instrumentation skills are a key asset to the success of NRG.
Prior to joining NRG, Xiaohui worked in a variety of research positions. He began as a postdoctoral research associate at the University of Mississippi, where he conducted bioassay guided isolation of antifungal compounds from microorganisms and marine sponges, as well as the structural modification of antifungal natural products. Xiaohui went on to build his career as a natural product chemist in Canada, where he focused on the research and development of natural health products with central nervous system activities.
Xiaohui has a PhD in medicinal chemistry from Shanghai Institute of Materia Medica and a BSc in Chemistry from the Shadong Normal University in China. He is fluent in Mandarin and has contributed to an array of publications, including the Journal of Natural Products and Plant Medica.