Course Overview
This course focuses primarily on antimicrobials and antimicrobial susceptibility testing (AST). Learners study drug classes and their generations, modes of action and target sites, usual lethality (bactericidal vs bacteriostatic), spectrum of activity, toxicity and/or hypersensitivity. The history and evolution of AST in modern medicine is introduced. Current AST techniques, conventional and automated methods, as well as the screening and confirmation of mechanisms of antimicrobial resistance, are taught and practiced in the laboratory sessions. Reporting strategies recommended by the Clinical Laboratory Standards Institute (CLSI) are introduced. In preparation for the next course, Specimen Processing in the Microbiology Laboratory is introduced. Theory and laboratory practice emphasize safety and quality control. Collaborative laboratory workshops and assignments enhance critical thinking, problem solving, and team-based interpersonal skills. Learning is assessed through online learning activities, unit exams, laboratory practical activities and workshops, along with formal laboratory and theory exams.
Prerequisite(s)
- All Level 2 courses and MLSC 2309
Credits
3.5
- Not offered this term
- This course is not offered this term. Notify me to receive email notifications when the course opens for registration next term.
Learning Outcomes
Upon successful completion of this course, the student will be able to:
- perform, interpret and report antimicrobial susceptibility testing (AST) set-up by each of the following methods: macro and micro-broth dilution, disc diffusion and gradient diffusion.
- recognize the potential for antimicrobial resistance (AMR) and set up, read, interpret and report common antimicrobial resistance mechanisms detected in select organisms.
- validate the results of the AST of common clinically significant organisms using calibrators, standards and quality control practices specific to the practice of clinical microbiology.
- recognize the role of the clinical laboratory in infection control, antimicrobial stewardship and regional and national AMR surveillance.
- practice safe laboratory techniques, including aseptic technique and biohazard spill cleanup, in the processing and testing of infectious materials including bacterial culture materials.
- work in an organized manner, prioritizing testing into routine, urgent and critical categories.
- maintain legible, accurate records of work performance, being mindful of medico-legal parameters.
- perform all laboratory testing in a safe, efficient and resourceful manner.
Effective as of Fall 2025
Related Programs
Clinical Microbiology 3 (MLSC 3309) is offered as a part of the following programs:
School of Health Sciences
- Medical Laboratory Science
Diploma Full-time
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