Carol Friedrich Fong

Carol_Fong@bcit.ca

work experience

Dr. Carol Friedrich-Fong is currently the Program Head and an instructor of Biotechnology and Molecular Genetics in the Biotechnology program at BCIT.

Carol obtained her honours Bachelor of Science degree in Microbiology at the University of Alberta. During her studies, she was involved in molecular biology and environmental microbiology research projects. After graduation, she worked at the German Institute of Human Nutrition where she conducted enzymology research as part of an international exchange program.


Carol received her PhD from the Department of Microbiology/Immunology at the University of British Columbia under the direction of Dr. Robert E. Hancock. Her research focused on the structure/function relationships of novel antimicrobial peptides and their mechanism of action on gram positive bacteria.

She continued with a post-doctoral position at Health Canada in Burnaby for 2 years prior to accepting a position as Instructor at BCIT. Carol has been an Instructor for various courses such as Microbiology for Nursing, Microbiology for Nuclear Medicine, Microbiology for Environmental Health, Regulatory Affairs and Laboratory Safety. In addition, she has been involved in curriculum development and has also acted as Program Coordinator of the Biotechnology Associate Certificate program and the Career Awareness high school workshop.

education

1995 - Honours BSc. Microbiology, University of Alberta

2001 PhD Microbiology and Immunology, University of British Columbia

2004 Visiting Fellow, Health Canada in Burnaby, BC

publications

Rozek, A., Powers, J.P., Friedrich, C.L. and R.E.W. Hancock. 2003. Structure-based design of an indolicidin peptide analogue with increased protease stability. Biochemistry 42(48):14130-8.

Patryzkat, A., C.L Friedrich, L. Zhang, V. Mendoza and R.E.W. Hancock. 2002. Sub letal concentrations of pleurocidin-derived antimicrobial peptides inhibit macromolecular synthesis in E. coli. Antimicrob. Agents Chemother. 46(3): 605-14.

Friedrich, C.L., A. Rozek, A. Patryzkat, and R.E.W. Hancock. 2001. Characterization of the structure and mechanism of action of an indolicidin derivative with improved activity against gram positive bacteria. Journal of Biological Chemistry. 276(26): 24015-22.

Friedrich, C.L., D. Moyles, T.J. Beveridge and R.E.W. Hancock. 2000 Antimicrobial action of structurally diverse cationic peptides on gram positive bacteria. Antimicrob. Agents Chemother. 44(8): 2086-2092.

Rozek, A., C.L Friedrich, R.E.W. Hancock, 2000 Structure of the bovine antimicrobial peptide indolicidin bound to dodecylphophocholine and sodium dodecyl sulfate micelles. Biochemistry. 39(51): 15765-74.

Hancock, R.E.W., M. Scott, C.Friedrich, L.Zhang, H.Yan, P.Nair, A.Patrzykat, and A.Rozek. 1999. Cationic peptide antibiotics for use in treatment of Pseudomonas aeruginosa infections of cystic fibrosis patients. Clin. Microbiol. Infect. 5:S52-S53.

Friedrich, C., M.G. Scott, N. Karunaratne, H., Yan, and R.E.W. Hancock. 1999 Salt-resistant alpha-helical cationic antimicrobial peptides. Antimicrob. Agents Chemother. 43(7): 1542-1548.

Mauer, S., C. Friedrich, M. Leist, M. Maiorino, and R. Brigelius-Flohe. 1998. Attempt to differentiate between individual glutathione peroxidases in biological samples. Z. Ernahrungswiss. 37 (Suppl 1): 110-3.