Publications

News

High-tech cannabis research supports quality control. BCIT News. May 10, 2018.

Vancouver researchers take issue with U.S. FDA's alarmist memo on kratom. Georgia Straight. Feb 17, 2018.

Journals

EM Mudge, PN Brown (2017) Determination of Mitragynine in Mitragyna speciosa Raw Materials and Finished Products by Liquid Chromatography with UV Detection: Single-Laboratory Validation. Journal of AOAC International. 100 (1).

Solyom et Al
(2016) Standard Method Performance Requirements for Quantitation of Curcuminoids 2016.003. Journal of AOAC International. 99 (4).

EM Mudge, Y Liu, JA Lund, PN Brown
(2016) Single Laboratory Validation for the Determination of Flavonoids in Hawthorn Leaves and Finished Products by LC-UV. Planta Medica. Oct 24.

EM Mudge, JM Betz, PN Brown
(2016) The Importance of Method Selection in Determining Product Integrity for Nutrition Research. Advances in Nutrition. Mar 15;7(2):390-8.

PN Brown, EM Mudge, L Paley (2016) Determination of Phenolic Constituents in Echinacea Raw Materials and Dietary Supplements by HPLC–UV: Collaborative Study. Journal of AOAC International. 99 (5):

A Diane, F Borthwick, S Wu, J Lee, PN Brown, TA Dickinson, KD Croft, DF Vine, SD Proctor
(2016) Hypolipidemic and cardioprotective benefits of a novel fireberry hawthorn fruit extract in the JCR:LA-cp rodent model of dyslipidemia and cardiac dysfunction. Food and Function. Sep 14;7(9):3943-52.

EM Mudge, WL Applequist, J Finley, P Lister, AK Townesmith, KM Walker, PN. Brown (2016) Variation of select flavonols and chlorogenic acid content of elderberry collected throughout the Eastern United States. Journal of Food Composition and Analysis. 47. p.52-59.

AMP Jones, MR Shukla, SM Sherif, PN Brown, PK Saxena (2016) Growth regulating properties of isoprene and isoprenoid-based essential oils. Plant Cell Reports. Jan;35 (1):91-102.

WB Glover, TC Baker, SJ Murch, PN Brown (2015) Determination of β-N-methylamino-L-alanine, N-(2-aminoethyl)glycine, and 2,4-diaminobutyric acid in Food Products Containing Cyanobacteria by Ultra-Performance Liquid Chromatography and Tandem Mass Spectrometry: Single-Laboratory Validation. Journal of AOAC International, 98 (6): 1559-1565.

EM Mudge, M Chan, S Venkataraman, PN Brown (2015). Curcuminoids in Turmeric Roots and Supplements: Method Optimization and Validation. Food Analytical Methods. Sept. p. 1-8.

EM Mudge, AMP Jones, PN Brown
(2015) Quantification of pyrrolizidine alkaloids in North American plants and honey by LC-MS: single laboratory validation. Food Additives & Contaminants. Dec 32 (12) 2068-2074.

EM Mudge, L Paley, A Schieber, PN Brown
(2015). Optimization and single-laboratory validation of a method for the determination of flavonolignans in milk thistle seeds by high-performance liquid chromatography with ultraviolet detection. Analytical and Bioanalytical Chemistry Chemistry, 407 (25): 7657-7666.

EM Mudge, L Paley, A Schieber, PN Brown (2015).
Optimization and single-laboratory validation of a method for the determination of flavonolignans in milk thistle seeds by high-performance liquid chromatography with ultraviolet detection. Analytical and Bioanalytical Chemistry Chemistry, 407 (25): 7657-7666.

H Zhou, Z Qu, VV Mossine, DL Nknolise, J Li, Z Chen; J Cheng; CM Greenlief, TP Mawhinney; PN Brown, KL Fritsche, M Hannink; DB Lubahn, GY Sun; Z Gu
(2014) Proteomic analysis of the effects of aged garlic extract and its FruArg component on lipopolysaccharide-induced neuroinflammatory response in microglial cells. PLoS One, 24; 9 (11): 1-25.

PN Brown, R Yu, CH Kuan, J Finley, EM Mudge, S Dentali
. (2014) Determination of Aloin A and Aloin B in Aloe vera Raw Materials and Finished Products by High-Performance Liquid Chromatography: Single-Laboratory Validation. Journal of AOAC International, 97 (5): 1323-1328.

PN Brown, P Lister
(2014). Current initiatives for the validation of analytical methods for botanicals.Current Opinion in Biotechnology, 25: 124-128.

PN Brown, JM Betz, FL Jaksch
(2013). How to Qualify an Analytical Laboratory for Analysis of Herbal Dietary Ingredients and Avoid Using a "Dry Lab". A review of issues related to using a contract analytical laboratory by industry, academia, and regulatory agencies. Herbal Gram, 99: 52-59.

PN Brown, R Yu (2013). Determination of ginsenoside content in Panax ginseng C.A. Meyer and Panax quinquefolius L. root materials and finished products by high-performance liquid chromatography with ultraviolet absorbance detection: Interlaboratory study. Journal of AOAC International, 96 (1): 12-19.

EM Mudge, D Lopes-Lutz , PN Brown, A Schieber
(2013). Purification of phenylalkanoids and monoterpene glycosides from Rhodiola rosea L. Roots by high-speed counter-current chromatography. Phytochemical Analysis. 24 (2): 129-134.

Published Abstracts

L Benkrima, EM Mudge, PN Brown (2014): Wasabi as a New Greenhouse Crop for BC and its Potential as a Functional Food and Natural Health Product. Journal of Pharmacy and Pharmaceutical Sciences, 17(4): 120s.

B Glover, PN Brown, SJ Murch (2014): Challenges and Opportunities in the Detection and Quantification of BMAA. Journal of Pharmacy and Pharmaceutical Sciences, 17(4): 132s.

C Turi, J Finley, PN Brown, SJ Murch (2014). Metabolomics as an Exploratory Tool for Natural Health Products Research. Journal of Pharmacy and Pharmaceutical Sciences, 17(4): 136s.

Books and monographs

PN Brown, R. Yu (contributing reviewer) Analytical Substantiating Laboratories: High Performance Liquid Chromatography, American Herbal Pharmacopoeia and Therapeutic Compendium: Standards of Analysis, Quality Control and Therapeutics. Cranberry fruit. Upton, R.(ed.), AHP, Santa Cruz, CA, 2016.

PN Brown, M. Chan, JM Betz (contributing authors). Chapter 2 - The Importance of Proper Selection of Product Quality Specifications and Methods of Analysis for Botanical Product Evaluation. Botanicals – Methods and Techniques for Quality & Authenticity. Reynertson, KA, Mahmood K (ed.), CRC Press, Boca Raton, FL, 33487-2742, 2015.

PN Brown (contributing reviewer) Analytical Substantiating Laboratories: High Performance Liquid Chromatography, American Herbal Pharmacopoeia and Therapeutic Compendium: Standards of Identity, Analysis and Quality Control. Cannabis Inflorescence. Upton, R.(ed.), AHP, Santa Cruz, CA, 2014.