Covers the use of GC-MS in chemical analysis. The course starts with a general discussion of the theory of mass spectrometry as applied to the field of GC-MS. Types of GC-MS are then compared. Subsequent sections of the course cover topics that relate to more advanced aspects of GC-MS including instrument components, modes of operation and the interpretation of GC-MS spectra. Other topics discussed include the optimization of quantitative and qualitative analyses using GC-MS and routine troubleshooting and maintenance of selected GC-MS instruments. Laboratory exercises provide practical training of the principles covered in the lectures. Prerequisite: Extensive GC knowledge or CHEM 5001.
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